Publications in 2023

Kobayashi M, Yoshimoto M*. Multiple waves of fetal-derived immune cells constitute adult immune system. Immunol Rev2023. 10.1111/imr.13192

Kobayashi M, Wei H, Yamanashi T, Azevedo Portilho N, Cornelius S, Valiente N, Nishida C, Cheng H, Latorre A, Zheng WJ, Kang J, Seita J, Shih DJ, Wu JQ, Yoshimoto M*. HSC-independent definitive hematopoiesis persists into adult life. Cell Rep. 42(3):112239, 2023. PMC10122268 10.1016/j.celrep.2023.112239

Lin Y, Banno K, Gil CH, Myslinski J, Hato T, Shelley WC, Gao H, Xuei X, Liu Y, Basile D, Yoshimoto M, Prasain N, Tarnawsky SP, Adams RH, Naruse K, Yoshida J, Murphy MP, Horie K, Yoder MC. Origin, prospective identification, and function of circulating endothelial colony forming cells in mouse and man. JCI Insight. 2023.

Abe JI, Imanishi M, Li S, Zhang A, Ko KA, Samanthapudi VSK, Lee LL, Bojorges AP, Gi YJ, Hobbs BP, Deswal A, Herrmann J, Lin SH, Chini EN, Shen YH, Schadler KL, Nguyen TH, Gupte AA, Reyes-Gibby C, Yeung SJ, Abe RJ, Olmsted-Davis EA, Krishnan S, Dantzer R, Palaskas NL, Cooke JP, Pownall HJ, Yoshimoto M, Fujiwara K, Hamilton DJ, Burks JK, Wang G, Le NT, Kotla S. An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis. Circ Res. 2023;133(1):25-44.

Publications in 2022

Yoshimoto M*, Kosters A, Cornelius S, et al. Mast Cell Repopulating Ability Is Lost During the Transition From Pre-HSC to FL HSC. Frontiers in Immunology. 2022;13.

Banerjee P, Olmsted-Davis EA, Deswal A, Nguyen MT, Koutroumpakis E, Palaskas NL, Lin SH, Kotla S, Reyes-Gibby C, Yeung SJ, Yusuf SW, Yoshimoto M, Kobayashi M, Yu B, Schadler K, Herrmann J, Cooke JP, Jain A, Chini E, Le NT, Abe JI. Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications. J Cardiovasc Aging. 22022. PMC9258520 10.20517/jca.2022.13

Imanishi M, Cheng H, Kotla S, Deswal A, Le NT, Chini E, Ko KA, Samanthapudi VSK, Lee LL, Herrmann J, Xu X, Reyes-Gibby C, Yeung SJ, Schadler KL, Yusuf SW, Liao Z, Nurieva R, Amir ED, Burks JK, Palaskas NL, Cooke JP, Lin SH, Kobayashi M, Yoshimoto M, Abe JI. Radiation therapy induces immunosenescence mediated by p90RSK. Front Cardiovasc Med. 2022;9:988713.

Publications in 2021

Azevedo Portilho N, Scarfo R, Bertesago E, Ismailoglu I, Kyba M, Kobayashi M, Ditadi A, Yoshimoto M. B1 lymphocytes develop independently of Notch signaling during mouse embryonic development. Development. 148(15)2021. PMC8380455

Ding J, Cardoso A. A, Yoshimoto M*, Kobayashi M.* The earliest T-precursors in the mouse embryo are susceptible to leukemic transformation. Frontiers in Cell and Developmental Biology. (2021) https://doi.org/10.3389/ fcell.2021.634151

Lewis K, Yoshimoto M, Takebe T. Fetal liver hematopoiesis: from development to delivery. Stem Cell Res Ther.12:139, (2021)

Publications in 2020

Kobayashi M, Lin Y, Mishra A, Shelly C, Gao R, Reeh CW, Wang PZ, Xi R, Liu Y, Wenzel P, Ghosn E, Liu Y, Yoshimoto M. Bmi1 Maintains the Self-Renewal Property of Innate-like B Lymphocytes. J Immunol. 204:3262-3272, (2020)

Yoshimoto M. The ontogeny of murine B-1a cells. Int J Hematol.111:622-627, (2020)

Publications in 2019

Yoshimoto M. B-1 progenitor acute lymphoid leukemia. Blood.133:2557-2558, (2019)

Lin Y, Kobayashi M, Azevedo Portilho N, Mishra A, Gao H, Liu Y, Wenzel P, Davis B, Yoder MC, Yoshimoto M. Long-Term Engraftment of ESC-Derived B-1 Progenitor Cells Supports HSC-Independent Lymphopoiesis. Stem Cell Reports.12:572-583, (2019) PMC6409422

Kobayashi M, Tarnawsky SP, Wei H, Mishra A, Azevedo Portilho N, Wenzel P, Davis B, Wu J, Hadland B, Yoshimoto M. Hemogenic Endothelial Cells Can Transition to Hematopoietic Stem Cells through a B-1 Lymphocyte-Biased State during Maturation in the Mouse Embryo. Stem Cell Reports.13:21-30, (2019) PMC6626887

Ghosn E, Yoshimoto M, Nakauchi H, Weissman IL, Herzenberg LA. Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes. Development.146(2019)

Ghosn E, Dorshkind K, Herzenberg LA, Holodick N, Kantor A, Montecino-Rodriguez E, Rothstein TL, Silverman GJ, Yang Y, Yoder MC, Yoshimoto M. B1 B cell progenitors. Science.364:248, (2019)

Selected Publications before 2018

Spidale NA, Sylvia K, Narayan K, Miu B, Frascoli M, Melichar HJ, Zhihao W, Kisielow J, Palin A, Serwold T, Love P, Kobayashi M, Yoshimoto M, Jain N, Kang J. Interleukin-17-Producing gammadelta T Cells Originate from SOX13(+) Progenitors that Are Independent of gammadeltaTCR Signaling. Immunity.49:857-872 e855, (2018) PMC6249057

Hadland B, Yoshimoto M. Many layers of embryonic hematopoiesis: new insights into B-cell ontogeny and the origin of hematopoietic stem cells. Exp Hematol.60:1-9, (2018) PMC5857217

Tarnawsky SP, Yoshimoto M, Deng L, Chan RJ, Yoder MC. Yolk sac erythromyeloid progenitors expressing gain of function PTPN11 have functional features of JMML but are not sufficient to cause disease in mice. Dev Dyn.246:1001-1014, (2017) PMCPMC5828034

Hadland BK, Varnum-Finney B, Mandal PK, Rossi DJ, Poulos MG, Butler JM, Rafii S, Yoder MC, Yoshimoto M, Bernstein ID. A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells. Stem Cell Reports.8:1563-1572, (2017) PMC5469918

Yoon J, Wang H, Kim YC, Yoshimoto M, Abbasi S, Morse Iii HC. Plasma cell alloantigen ENPP1 is expressed by a subset of human B cells with potential regulatory functions. Immunol Cell Biol.94:719-728, (2016)

Yoshimoto M, Koenig JM. Stem Cells: Potential Therapy for Neonatal Injury? Clin Perinatol.42:597-612, (2015) PMC4529537

Yoshimoto M. The first wave of B lymphopoiesis develops independently of stem cells in the murine embryo. Ann N Y Acad Sci.1362:16-22, (2015)

Prasain N, Lee MR, Vemula S, Meador JL, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MR, Ginsberg M, Elemento O, Lee Y, Voytik-Harbin SL, Chung HM, Hong KS, Reid E, O'Neill CL, Medina RJ, Stitt AW, Murphy MP, Rafii S, Broxmeyer HE, Yoder MC. Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells. Nat Biotechnol.32:1151-1157, (2014) PMC4318247

Lin Y, Yoder MC, Yoshimoto M. Lymphoid progenitor emergence in the murine embryo and yolk sac precedes stem cell detection. Stem Cells Dev.23:1168-1177, (2014) PMCPMC4028089

Kobayashi M, Shelley WC, Seo W, Vemula S, Lin Y, Liu Y, Kapur R, Taniuchi I, Yoshimoto M. Functional B-1 progenitor cells are present in the hematopoietic stem cell-deficient embryo and depend on Cbfbeta for their development. Proc Natl Acad Sci U S A.111:12151-12156, (2014) PMC4143017

Arora N, Wenzel PL, McKinney-Freeman SL, Ross SJ, Kim PG, Chou SS, Yoshimoto M, Yoder MC, Daley GQ. Effect of developmental stage of HSC and recipient on transplant outcomes. Dev Cell.29:621-628, (2014) PMC4172398

Swiers G, Baumann C, O'Rourke J, Giannoulatou E, Taylor S, Joshi A, Moignard V, Pina C, Bee T, Kokkaliaris KD, Yoshimoto M, Yoder MC, Frampton J, Schroeder T, Enver T, Gottgens B, de Bruijn M. Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level. Nat Commun.4:2924, (2013) PMC4362711

Yoshimoto M, Porayette P, Glosson NL, Conway SJ, Carlesso N, Cardoso AA, Kaplan MH, Yoder MC. Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence. Blood.119:5706-5714, (2012) PMC3382930

Choi E, Kraus MR, Lemaire LA, Yoshimoto M, Vemula S, Potter LA, Manduchi E, Stoeckert CJ, Jr., Grapin-Botton A, Magnuson MA. Dual lineage-specific expression of Sox17 during mouse embryogenesis. Stem Cells.30:2297-2308, (2012) PMC3448801

Yoshimoto M, Montecino-Rodriguez E, Ferkowicz MJ, Porayette P, Shelley WC, Conway SJ, Dorshkind K, Yoder MC. Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential. Proc Natl Acad Sci U S A.108:1468-1473, (2011) PMC3029764

Yoshimoto M, Yoder MC. Developmental biology: Birth of the blood cell. Nature.457:801-803, (2009) PMCPMC2766277

Yoshimoto M, Heike T, Chang H, Kanatsu-Shinohara M, Baba S, Varnau JT, Shinohara T, Yoder MC, Nakahata T. Bone marrow engraftment but limited expansion of hematopoietic cells from multipotent germline stem cells derived from neonatal mouse testis. Exp Hematol.37:1400-1410, (2009) PMC2944399

Adamo L, Naveiras O, Wenzel PL, McKinney-Freeman S, Mack PJ, Gracia-Sancho J, Suchy-Dicey A, Yoshimoto M, Lensch MW, Yoder MC, Garcia-Cardena G, Daley GQ. Biomechanical forces promote embryonic haematopoiesis. Nature.459:1131-1135, (2009) PMC2782763

Yoshimoto M, Porayette P, Yoder MC. Overcoming obstacles in the search for the site of hematopoietic stem cell emergence. Cell Stem Cell.3:583-586, (2008) PMC2756073